Structural design is an important aspect of civil engineering, focusing on safety, efficiency, and durability. This study discusses the application of the Load Resistance Factor Design (LRFD) method in designing the Bali Galeria Mall, a shopping center with high architectural complexity in Bali. LRFD combines load and resistance factors to address uncertainties in design, such as variations in materials and loads received by buildings during their service life, resulting in safer and more economical designs compared to other methods such as Allowable Stress Design (ASD). Technical data, including building plans, material types, and environmental conditions, were modeled using ETABS software with simulations to test the building's response to dead, live, and wind loads. The results show that the application of LRFD supported by ETABS meets safety and stability standards and is more efficient in material usage compared to ASD. The structural design includes 10-12 cm thick floor slabs, 900-1000 mm diameter columns, 400x600 to 600x750 beams, and 30 cm diameter bored pile foundations. In conclusion, the LRFD method is highly effective for buildings with high complexity such as Mall Bali Galeria, ensuring safety and material efficiency in structural design.